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Invitrogen
CCNDBP1 Polyclonal Antibody
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产品信息
PA5-65285
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SPENNDLISYN SVWVACQQMP QIPRDNKAAA LLMLTKNVDF VKDAHEEMEQ AVEECDPYSG LLNDTEENNS DNHNHEDDVL GFPSNQD
Highest antigen sequence identity to the following orthologs - mouse 81%, rat 76%.
靶标信息
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cyclin D-type binding-protein 1; Cyclin-D1-binding protein 1; D-type cyclin-interacting protein 1; grap2 and cyclin D interacting protein; Grap2 and cyclin-D-interacting protein; Human homolog of Maid
基因别名: CCNDBP1; DIP1; GCIP; HHM
UniProt ID: (Human) O95273
Entrez Gene ID: (Human) 23582
