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Invitrogen
CCNK Polyclonal Antibody
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图: 1 / 2
CCNK Antibody (PA5-114710) in ICC/IF
Immunocytochemistry analysis of CCNK in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114710). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114710
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CCNK(Accession O75909), corresponding to amino acid residues M1-L38.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CCNK.
靶标信息
Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
regulation of cyclin-dependent protein serine/threonine kinase activity
in utero embryonic development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
cellular response to DNA damage stimulus
cell cycle
mitotic nuclear division
negative regulation by host of viral genome replication
cell division
negative regulation of cell cycle arrest
positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
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