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Invitrogen
CCRN4L Polyclonal Antibody
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CCRN4L Antibody (PA5-90719) in WB
Western blot analysis of CCRN4L in extracts of Rat brain. Samples were incubated with CCRN4L Polyclonal antibody (Product # PA5-90719) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-90719
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human NOCT (NP_0362502)
偶联物
形式
Liquid
浓度
1.66 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LRTDCPSTHP PIRVMQWNIL AQALGEGKDN FVQCPVEALK WEERKCLILE EILAYQPDIL CLQEVDHYFD TFQPLLSRLG YQGTFFPKPW SPCLDVEHNN GPDGCALFFL QNRFKLVNSA NIRLTAMTLK TNQVAIAQTL ECKESGRQFC IAVTHLKART GWERFRSAQG CDLLQNLQNI TQGAKIPLIV CGDFNAEPTE EVYKHFASSS LNLNSAYKLL SADGQSEPPY TTWKIRTSGE CRHTLDYIWY SKHALNVRSA LDLLTEEQIG PNRLPSFNYP SDHLSLVCDF SFTEESDGLS; Positive Samples: Rat brain; Cellular Location: Cytoplasm, Nucleus, perinuclear region
靶标信息
CCRN4L is highly similar to Nocturnin, identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carbon catabolite epression 4 homolog; carbon catabolite repression 4 homolog; Carbon catabolite repression 4-like protein; CCR4 carbon catabolite repression 4-like B; CCR4 protein homolog; circadian deadenylase NOC; MGC142054; MGC142060; MGC4120817; MGC78549; nocturin; Nocturnin
基因别名: AU043840; Ccr4; Ccrn4l; Ccrn4lb; Noc; Noct; nocturnin
UniProt ID: (Rat) Q9ET55, (Mouse) O35710
Entrez Gene ID: (Rat) 310395, (Mouse) 12457
deadenylation-dependent decapping of nuclear-transcribed mRNA
mRNA processing
response to extracellular stimulus
negative regulation of gene expression
response to lipopolysaccharide
circadian regulation of gene expression
cytoplasmic mRNA processing body assembly
regulation of circadian rhythm
positive regulation of fat cell differentiation
negative regulation of osteoblast differentiation
regulation of embryonic development
mRNA stabilization
RNA phosphodiester bond hydrolysis, exonucleolytic
rhythmic process
