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CD1.1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8 alpha+ cells. CD1.2 is expressed in TCR gamma delta cells but is nearly undetectable in TCR alpha beta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: a polypeptide; CD1-2 antigen; CD1.2 antigen; CD1A antigen, a polypeptide; CD1a molecule; CD1c; chCD1-2; T-cell surface glycoprotein CD1A2 antigen
基因别名: CD1.1; CD1.2; CD1A; CD1A2
Entrez Gene ID: (Chicken) 425802