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The CD1 is a family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD1a; CD1a antigen precursor; CD1A antigen, a polypeptide; CD1c; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; hTa1 thymocyte antigen; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a; unnamed protein product
基因别名: CD1; CD1A; FCB6; HTA1; R4; T6
UniProt ID: (Human) P06126
Entrez Gene ID: (Human) 909