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Invitrogen
CD109 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100711
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CD109(Accession Q6YHK3), corresponding to amino acid residues S1397-L1445.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CD109.
靶标信息
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; AMCOM; alpha2-macroglobulin/complement; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; Gov platelet alloantigens; GPI-anchored alpha 2 macroglobulin-related protein; GPI-anchored alpha-2 macroglobulin-related protein; GPI-anchored membrane protein; p180; Platelet-specific Gov antigen; r150; RP11-525G3.1; unnamed protein product
基因别名: 9930012E15Rik; AI480638; CD109; CPAMD7; GARP; p180; r150
UniProt ID: (Human) Q6YHK3, (Mouse) Q8R422
Entrez Gene ID: (Human) 135228, (Mouse) 235505
hair follicle development
negative regulation of keratinocyte proliferation
negative regulation of transforming growth factor beta receptor signaling pathway
keratinocyte proliferation
regulation of keratinocyte differentiation
negative regulation of wound healing
stem cell proliferation
osteoclast fusion
negative regulation of stem cell proliferation
negative regulation of protein phosphorylation
negative regulation of peptidase activity
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