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Invitrogen
CD109 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-139735
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: VVSGNKRLKE LSYMVVSRGQ LVAVGKQNST MFSLTPENSW TPKACVIVYY IEDDGEIISD VLKIPVQLVF KNKIKLYWSK VKAEPSEKVS LRISVTQPDS IVGIVAVDKS VNLMNASNDI TMENVVHEL
Highest antigen sequence indentity to the following orthologs: Mouse - 72%, Rat - 77%.
靶标信息
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; AMCOM; alpha2-macroglobulin/complement; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109; CD109 antigen; Gov platelet alloantigens; GPI-anchored membrane protein; p180; Platelet-specific Gov antigen; r150; RP11-525G3.1; unnamed protein product
基因别名: CD109; CPAMD7; p180; r150
UniProt ID: (Human) Q6YHK3
Entrez Gene ID: (Human) 135228
hair follicle development
negative regulation of keratinocyte proliferation
negative regulation of transforming growth factor beta receptor signaling pathway
keratinocyte proliferation
regulation of keratinocyte differentiation
negative regulation of wound healing
stem cell proliferation
osteoclast fusion
negative regulation of stem cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
