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Invitrogen
CD147 Recombinant Rabbit Monoclonal Antibody (23GB1460)
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图: 1 / 4
CD147 Antibody (MA5-54218) in ICC/IF
Immunocytochemistry analysis of CD147 in HepG2 cells. Nuclei were stained blue with DAPI; CD147 recombinant monoclonal antibody (Product # MA5-54218) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-54218
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB1460
抗原
A synthesized peptide derived from human CD147 (150-200AA).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5A11/Basigin; 5A11; immunoglobulin gene superfamily; adhesion molecule; amino acid feature: intracellular domain, aa 707 .. 829; amino acid feature: transmembrane domain, aa 638 .. 706; amino acid feature: extracellular domain, aa 86 .. 637; basic immunoglobulin superfamily; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); collagenase stimulatory factor; extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; hepatoma-associated antigen; HT7 antigen; leukocyte activation antigen M6; member of immunoglobulin superfamily; membrane glycoprotein gp42; neurothelin; OK blood group antigen; OX-47 antigen; retinal glycoprotein; tumor cell-derived collagenase stimulatory factor; unnamed protein product
基因别名: 5A11; 5F7; basignin; CD147; CE9; EMMPRIN; EMPRIN; HAb18G; HT-7; HT7; OK; Ox47R; TCSF
UniProt ID: (Human) P35613, (Rat) P26453, (Mouse) P18572
Entrez Gene ID: (Human) 682, (Rat) 25246, (Mouse) 12215
neural retina development
homophilic cell adhesion via plasma membrane adhesion molecules
cell surface receptor signaling pathway
axon guidance
embryo implantation
anatomical structure morphogenesis
positive regulation of vascular endothelial growth factor production
positive regulation of endothelial cell migration
neutrophil chemotaxis
positive regulation of interleukin-6 production
odontogenesis of dentin-containing tooth
response to peptide hormone
photoreceptor cell maintenance
positive regulation of viral entry into host cell
response to mercury ion
decidualization
viral entry into host cell
response to cAMP
endothelial tube morphogenesis
dendrite self-avoidance
protein localization to plasma membrane
positive regulation of matrix metallopeptidase secretion
neuron projection extension
spermatogenesis
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