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Invitrogen
CD226 Recombinant Rabbit Monoclonal Antibody (102)
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产品信息
MA5-30167
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
102
抗原
Recombinant Human CD226 protein (Met1-Asn247)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CD226/DNAM-1.
靶标信息
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen
基因别名: CD226; DNAM-1; DNAM1; PTA1; TLiSA1
UniProt ID: (Human) Q15762
Entrez Gene ID: (Human) 10666
cytokine production
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
positive regulation of immunoglobulin mediated immune response
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
cell recognition
positive regulation of mast cell activation
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
positive regulation of Fc receptor mediated stimulatory signaling pathway
