Invitrogen

CD24 Monoclonal Antibody (SN3), PE

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CD24 Antibody (MA1-10154) in Flow

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-human CD24 (SN3) PE Monoclonal antibody (Product # MA1-10154).

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产品信息

MA1-10154

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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流式细胞分析 (Flow)

20 µL/1x10^6 cells

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SN3

抗原

Glycoproteins purified from human NALM-1 cell line.

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偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

纯化类型

Size-exclusion chromatography

保存液

PBS, pH 7.4, with 0.2% BSA

内含物

15mM sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_11153255

产品详细信息

This antibody reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.

靶标信息

CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Product References

Increased Steady-State Memory B Cell Subsets Among High-Risk Participants in an HIV Vaccine Trial.

AIDS research and human retroviruses

Keefer MC,Zheng B,Rosenberg AF,Kobie JJ

MA110154 was used in flow cytometry to investigate how differences in B cell populations may contribute to HIV susceptibility

Mon Dec 18 00:00:00 EST 2017

Tunicamycin-induced endoplasmic reticulum stress reduces in vitro subpopulation and invasion of CD44+/CD24- phenotype breast cancer stem cells.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie

Nami B,Donmez H,Kocak N

MA1-10154 was used in flow cytometry to learn about the reduction of an in vitro subpopulation and invasion of CD44+/CD24- phenotype breast cancer stem cells after tunicamycin-induced endoplasmic reticulum stress

Mon Aug 01 00:00:00 EDT 2016

Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users.

PloS one

Piepenbrink MS,Samuel M,Zheng B,Carter B,Fucile C,Bunce C,Kiebala M,Khan AA,Thakar J,Maggirwar SB,Morse D,Rosenberg AF,Haughey NJ,Valenti W,Keefer MC,Kobie JJ

MA110154 was used in flow cytometry to characterize B cells and antibody repertoires from injection drug users

Mon Jul 31 00:00:00 EDT 2017

CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

Histopathology

Ianez RC,Coutinho-Camillo CM,Buim ME,Pinto CA,Soares FA,Lourenço SV

MA1-10154 was used in immunohistochemistry to study whether CD24 and CD44 expression in salivary glands can be used as markers of cancer stem cells

Sat Jun 01 00:00:00 EDT 2013

Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.

BMC cancer

Ghebeh H,Sleiman GM,Manogaran PS,Al-Mazrou A,Barhoush E,Al-Mohanna FH,Tulbah A,Al-Faqeeh K,Adra CN

MA1-10154 was used in flow cytometry to determine the phenotype and function of stem/progenitor cells in normal mammary epithelial cell populations and their malignant counterparts

Fri Jun 14 00:00:00 EDT 2013

Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice.

Biochemical pharmacology

Takehara M,Hoshino T,Namba T,Yamakawa N,Mizushima T

MA1-10154 was used in immunohistochemistry to screen compounds able to induce differentiation of cancer stem cells

Sun May 01 00:00:00 EDT 2011

Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells.

Biochimica et biophysica acta

Rybak AP,He L,Kapoor A,Cutz JC,Tang D

MA1-10154 was used in immunohistochemistry to study sphere-propagating cells with stem-like properties from DU145 prostate cancer cells

Sun May 01 00:00:00 EDT 2011

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research

Tanei T,Morimoto K,Shimazu K,Kim SJ,Tanji Y,Taguchi T,Tamaki Y,Noguchi S

MA1-10154 was used in immunohistochemistry to study whether cancer stem cells are clinically significant for resistance to chemotherapy in human breast cancers

Mon Jun 15 00:00:00 EDT 2009

CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery.

Clinical cancer research : an official journal of the American Association for Cancer Research

Yang XR,Xu Y,Yu B,Zhou J,Li JC,Qiu SJ,Shi YH,Wang XY,Dai Z,Shi GM,Wu B,Wu LM,Yang GH,Zhang BH,Qin WX,Fan J

MA1-10154 was used in immunohistochemistry to study the role of CD24 in tumor invasion and its prognostic significance in hepatocellular carcinoma

Tue Sep 01 00:00:00 EDT 2009

A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950)

Wei C,Anolik J,Cappione A,Zheng B,Pugh-Bernard A,Brooks J,Lee EH,Milner EC,Sanz I

MA1-10154 was used in flow cytometry to discuss the frequency and contribution of CD27- memory B cells to systemic lupus erythematosus

Tue May 15 00:00:00 EDT 2007

Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli.

Nephron. Experimental nephrology

Bennett MR,Czech KA,Arend LJ,Witte DP,Devarajan P,Potter SS

MA1-10154 was used in immunohistochemistry to analyse the focal segmental glomerulosclerosis glomeruli by laser capture microdissection-microarray method

Tue Oct 02 00:00:00 EDT 2007

CD24 expression is a prognostic factor in intrahepatic cholangiocarcinoma.

Cancer letters

Su MC,Hsu C,Kao HL,Jeng YM

MA1-10154 was used in immunohistochemistry to study CD24 expression as a prognostic factor in intrahepatic cholangiocarcinoma

Sat Apr 08 00:00:00 EDT 2006

Cytoplasmic CD24 expression in colorectal cancer independently correlates with shortened patient survival.

Clinical cancer research : an official journal of the American Association for Cancer Research

Weichert W,Denkert C,Burkhardt M,Gansukh T,Bellach J,Altevogt P,Dietel M,Kristiansen G

MA1-10154 was used in immunohistochemistry to study the prognostic value of cytoplasmic CD24 expression in colorectal cancer

Thu Sep 15 00:00:00 EDT 2005

Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival.

The Journal of pathology

Kristiansen G,Pilarsky C,Wissmann C,Kaiser S,Bruemmendorf T,Roepcke S,Dahl E,Hinzmann B,Specht T,Pervan J,Stephan C,Loening S,Dietel M,Rosenthal A

MA1-10154 was used in immunohistochemistry to profile the expression patterns of microdissected prostate cancer samples to identify new prognostic markers

Tue Feb 01 00:00:00 EST 2005

CD24 expression is a significant predictor of PSA relapse and poor prognosis in low grade or organ confined prostate cancer.

The Prostate

Kristiansen G,Pilarsky C,Pervan J,Stürzebecher B,Stephan C,Jung K,Loening S,Rosenthal A,Dietel M

MA1-10154 was used in immunohistochemistry to study the prognostic value of CD24 expression in low grade or organ confined prostate cancer

Sun Feb 01 00:00:00 EST 2004

生物信息学

蛋白别名: CD24; CD24 antigen (small cell lung carcinoma cluster 4 antigen); FLJ22950; FLJ43543; MGC75043; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen

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基因别名: CD24; CD24A

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UniProt ID: (Human) P25063

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Entrez Gene ID: (Human) 100133941

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功能

signal transducer activity protein binding protein kinase binding protein tyrosine kinase activator activity

参与通路