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Invitrogen
CD3/CD44 Antibody Cocktail, FITC, PE
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Product Details
MA1-12273
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Cocktail
Type
Antibody
Clone
M2AB, 7F1
Immunogen
human thymocytes and TCR-gamma epsilon thymocytes
Conjugate
FITC , PE
FITC , PE
FITC , PE
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.2% carrier protein
Contains
0.08% sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is a monoclonal mixture of FITC-conjugated CD3 (clone M2AB, isotype IgG1) and PE-conjugated CD44 (clone 7F1, isotype IgG1).
Target Information
CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD3 epsilon; CD3d; CD3e; CD3g; CD44; CD44 antigen; CD44 molecule; CDw44; ECMR-III; ECMRIII; Epican; Extracellular matrix receptor III; FLJ18683; GP90 lymphocyte homing/adhesion receptor; HCAM; Heparan sulfate proteoglycan; Hermes antigen; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; PGP I; PGP-1; PGP-I; PGPI; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; sCD 44; sCD44; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain
Gene Aliases: CD3D; CD3E; CD3G; CD44; LHR; MDU2; MDU3; MIC4; T3D; T3E; T3G
Entrez Gene ID: (Human) 915, (Human) 916, (Human) 917, (Human) 960
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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