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Invitrogen
CD3/HLA Class 2 Antibody Cocktail, FITC, PE
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产品信息
MA5-16958
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1/IgG2a
分类
Cocktail
类型
Antibody
克隆号
UCHT1/WR18
抗原
Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome, Human B-CLL cells
偶联物
FITC , PE
FITC , PE
FITC , PE
形式
Lyophilized
浓度
Conc. Not Determined
纯化类型
purified
保存液
PBS with 1% BSA, 5% sucrose
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-16958 contains a monoclonal mixture of FITC-conjugated CD3 (clone #UCH-T1, Mouse IgG1) and RPE-conjugated HLA Class 2 (clone #WR18, Mouse IgG2a). UCHT1 recognizes the human CD3 cell surface antigen expressed by T lymphocytes. WR18 recognizes a common determinant on the beta chain of the human HLA Class 2 molecules HLA-DR, DP and DQ. This antigen is expressed on B lymphocytes, monocytes and on activated T lymphocytes. This antibody is designed to permit the simultaneous enumeration of CD3 and HLA Class 2 expressing cells. It is particularly useful in the assessment of HLA Class 2 expression on T lymphocytes.
Reconstitute with 0.5 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
靶标信息
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD3 epsilon; CD3d; CD3e; CD3g; CD74 antigen; DHLAG; FLJ18683; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA class II histocompatibility antigen, DRB1 beta chain; HLA-DQ; HLA-DR-gamma; HLA-DRB1; HLADG; Human leukocyte antigen DRB1; IA-gamma; MHC class II antigen DPB1; MHC class II antigen DQB1; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain
基因别名: CD3D; CD3E; CD3G; HLA-DP1B; HLA-DPB1; HLA-DQB; HLA-DQB1; HLA-DRB1; T3D; T3E; T3G
Entrez Gene ID: (Human) 915, (Human) 916, (Human) 917, (Human) 3115, (Human) 3119, (Human) 3123
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