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Invitrogen
CD300b Polyclonal Antibody
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产品信息
PA5-68464
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human CD300b [aa 61-110].
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Human samples.
靶标信息
CD300 molecule-like family member b (CD300LB), also known as CLM-7, is a gene located on chromosome 17q25.1, encoding an immunoreceptor that belongs to the CD300 family of molecules. CD300LB is primarily expressed on the surface of myeloid cells, including dendritic cells and macrophages, where it plays an essential role in modulating immune responses. The receptor is involved in the regulation of cell activation and inflammatory responses through its interactions with phosphatidylserine and other lipid ligands, which can lead to either activation or inhibition of immune cell functions. CD300LB influences processes like antigen presentation, phagocytosis, and cytokine production, thereby impacting innate immune responses and the maintenance of immune homeostasis. Its expression and activity are of particular interest in contexts like autoimmunity, infection, and cancer, where it may contribute to disease progression and serve as a potential therapeutic target in modulating immune functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen like family member B; CD300 antigen-like family member B; CD300 molecule-like family member b; CD300b; CLM-7; CMRF35-A2; CMRF35-like molecule 7; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; TREM-5; Triggering receptor expressed on myeloid cells 5
基因别名: CD300B; CD300LB; CLM-7; CLM7; CMRF35-A2; CMRF35A2; IREM-3; IREM3; LMIR5; TREM-5; TREM5; UNQ2530/PRO6029
UniProt ID: (Human) A8K4G0
Entrez Gene ID: (Human) 124599
