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Invitrogen
CD300g Polyclonal Antibody
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CD300g Antibody (PA5-106823) in ICC/IF
Immunocytochemistry analysis of CD300g in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CD300g polyclonal antibody (Product # PA5-106823) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-106823
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CD300LG(Accession Q6UXG3), corresponding to amino acid residues A168-M218.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CD300LG.
靶标信息
CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule-like family member g; CD300g; CD300g antigen; CLM-9; CLM9Trem4; CMRF-35-like molecule-9; CMRF35-like molecule 9; Nepmucin; TREM-4; Triggering receptor expressed on myeloid cells 4
基因别名: 2310016B05Rik; CD300LG; CLM-9; CLM9; D11Ertd736e; NEPMUCIN; TREM-4; TREM4; UNQ422/PRO846
UniProt ID: (Human) Q6UXG3, (Mouse) Q1ERP8
Entrez Gene ID: (Human) 146894, (Mouse) 52685
