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Invitrogen
CD300g Polyclonal Antibody
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FIGURE: 1 / 3
CD300g Antibody (PA5-117675) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of CD300g in 293 cells using CD300g Polyclonal Antibody (Product # PA5-117675) diluted at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product Details
PA5-117675
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CMRF35-like molecule 9 protein (128-241aa)
Conjugate
Form
Liquid
Concentration
2.99 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule-like family member g; CD300g; CD300g antigen; CLM-9; CLM9Trem4; CMRF35-like molecule 9; TREM-4; Triggering receptor expressed on myeloid cells 4
Gene Aliases: CD300LG; CLM-9; CLM9; NEPMUCIN; RGD1311074; TREM-4; TREM4; UNQ422/PRO846
UniProt ID: (Human) Q6UXG3
Entrez Gene ID: (Human) 146894, (Rat) 684984
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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