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Invitrogen
CD300g Recombinant Rabbit Monoclonal Antibody (102)
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产品信息
MA5-30254
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
102
抗原
Recombinant Human CLM-9/TREM4 Protein (Met1-Arg247)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CLM-9/TREM4.
靶标信息
CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen like family member G; CD300 antigen-like family member G; CD300 molecule-like family member g; CD300g; CD300g antigen; CLM-9; CLM9Trem4; CMRF35-like molecule 9; TREM-4; Triggering receptor expressed on myeloid cells 4
基因别名: CD300LG; CLM-9; CLM9; NEPMUCIN; TREM-4; TREM4; UNQ422/PRO846
UniProt ID: (Human) Q6UXG3
Entrez Gene ID: (Human) 146894
