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Invitrogen
CD41/CD61 Monoclonal Antibody (PAC-1), Alexa Fluor™ 647
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CD41/CD61 Antibody (MA562319) in Flow
Flow cytometry (surface staining) of CD41/CD61 in human PHA stimulated peripheral whole blood. Samples were stained with CD41/CD61 monoclonal antibody (Product # MA562319) using a dilution of 9 µg/mL. Separation of human CD41/CD61 positive CD45 negative activated thrombocytes (red-filled) from CD41/CD61 negative CD45 positive lymphocytes (black-dashed).
产品信息
MA562319
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgM, kappa
分类
Monoclonal
类型
Antibody
克隆号
PAC-1
抗原
Human platelets.
偶联物
激发/发射光谱
650/671 nm
查看光谱
形式
Liquid
纯化类型
Size-exclusion chromatography
保存液
TBS, pH 8, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: alphaIIb protein; antigen CD61; CD41; CD61; GPalpha IIb; GPIIb; GPIIIa; Integrin alpha-2b; Integrin alpha-IIb; integrin beta 3; Integrin beta-3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93
基因别名: BDPLT16; BDPLT2; CD41; CD41B; CD61; GP2B; GP3A; GPIIb; GPIIIa; GT; GTA; HPA3; ITGA2B; ITGAB; ITGB3; PPP1R93
UniProt ID: (Human) P08514, (Human) P05106
Entrez Gene ID: (Human) 3674, (Human) 3690
protein binding
identical protein binding
metal ion binding
extracellular matrix binding
fibrinogen binding
virus receptor activity
fibronectin binding
protease binding
protein disulfide isomerase activity
platelet-derived growth factor receptor binding
coreceptor activity
fibroblast growth factor binding
enzyme binding
C-X3-C chemokine binding
insulin-like growth factor I binding
neuregulin binding
vascular endothelial growth factor receptor 2 binding
cell adhesion molecule binding
integrin
platelet degranulation
positive regulation of leukocyte migration
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
extracellular matrix organization
platelet aggregation
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
cell-substrate junction assembly
blood coagulation
positive regulation of endothelial cell migration
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
smooth muscle cell migration
cell growth
cell migration
platelet activation
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
activation of protein kinase activity
negative regulation of lipid transport
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
tube development
apolipoprotein A-I-mediated signaling pathway
wound healing
regulation of bone resorption
negative regulation of low-density lipoprotein particle receptor biosynthetic process
viral entry into host cell
vascular endothelial growth factor receptor signaling pathway
mesodermal cell differentiation
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipoprotein metabolic process
leukocyte migration
negative chemotaxis
angiogenesis involved in wound healing
