Invitrogen

CD45RC Monoclonal Antibody (3a56), PE

Name: CD45RC Monoclonal Antibody (3a56), PE
Brand: Invitrogen
SKU: MA5-41036

查看其他12个CD45RC抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA5-41036

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Neat-1:10

产品规格

种属反应

Pig

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

3a56

偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Lyophilized

纯化类型

Protein A

保存液

PBS with 1% BSA, 5% sucrose

内含物

0.09% sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_2898790

产品详细信息

Reconstitute by adding 1 mL distilled water.

靶标信息

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.

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