Invitrogen

CD45RC Monoclonal Antibody (MIL15)

Name: CD45RC Monoclonal Antibody (MIL15)
Brand: Invitrogen
SKU: MA1-82383

查看其他12个CD45RC抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA1-82383

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组化（冰冻） (IHC (F))

Assay-dependent

流式细胞分析 (Flow)

Neat

产品规格

种属反应

Pig

宿主/亚型

Mouse / IgM

分类

Monoclonal

类型

Antibody

克隆号

MIL15

抗原

Cells isolated from porcine mesenteric lymph node.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

tissue culture supernatant with 5-10% FBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_928466

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti Pig CD45RC, clone MIL5 recognizes a restricted CD45 epitope encoded by the CD45 C exon and will bind and immunoprecipitate both the approximately 210 kDa RC and approximately 226 kDa RAC isoforms.

靶标信息

CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。