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Invitrogen
CD49e (Integrin alpha 5) Polyclonal Antibody
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CD49e (Integrin alpha 5) Antibody (PA5-79529) in IHC (P)
Immunohistochemistry (Paraffin) analysis of CD49e (Integrin alpha 5) in paraffin-embedded section of human placenta tissue using CD49e (Integrin alpha 5) Polyclonal Antibody (Product # PA5-79529). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibod... View More
产品信息
PA5-79529
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human Integrin alpha 5 recombinant protein (Position: F42-A263).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human A549 whole cell lysates, human Hela whole cell lysates, human placenta tissue lysates, rat brain tissue lysates, rat PC-12 whole cell lysates, mouse brain tissue lysates. IHC: human placenta tissue, rat bladder tissue .
靶标信息
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); Integrin alpha-5; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5
基因别名: CD49e; FNRA; ITGA5; Itga5_retired; VLA-5; VLA5; VLA5A
UniProt ID: (Human) P08648, (Mouse) P11688
Entrez Gene ID: (Human) 3678, (Mouse) 16402, (Rat) 315346
angiogenesis
cell-substrate junction assembly
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
leukocyte cell-cell adhesion
integrin-mediated signaling pathway
memory
positive regulation of cell-substrate adhesion
extracellular matrix organization
positive regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
cell-substrate adhesion
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
wound healing, spreading of epidermal cells
endodermal cell differentiation
viral entry into host cell
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte migration
positive regulation of sprouting angiogenesis
negative regulation of anoikis
