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Invitrogen
CD52 Chimeric Recombinant Human Monoclonal Antibody (Campath-1H)
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CD52 Chimeric Antibody (MA5-47771) in IHC (P)
Immunohistochemistry analysis of CD52 in fixed rat thymus tissue using CD52 Recombinant Monoclonal Antibody (Product # MA5-47771) at a concentration of 5 µg/mL followed by a FITC conjugated secondary antibody, showing membrane and cytoplasmic staining of a subset of cells. The nuclear stain is DAPI (blue). Panels show from left-right: primary antibody, DAPI and merged channels.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-47771
应用
建议稀释比
已发表文章
产品规格
种属反应
Cynomolgus monkey,
Human,
Rhesus monkey
宿主/亚型
Human
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
Campath-1H
抗原
Human lymphocytes.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
200 µg
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specificity: Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.
靶标信息
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CDw52; epididymal CAMPATH-1 antigen,epididymal CDw52 antigen; Epididymal secretory protein E5; He5; Human epididymis-specific protein 5
基因别名: CD52; CDW52; EGK_00417; HE5
UniProt ID: (Cynomolgus monkey) P32763
Entrez Gene ID: (Rhesus monkey) 714429, (Cynomolgus monkey) 102144354
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