Invitrogen

CD62E/CD62P Monoclonal Antibody (1.2B6), PE-Cyanine5

Name: CD62E\/CD62P Monoclonal Antibody (1.2B6), PE-Cyanine5
Brand: Invitrogen
SKU: MA5-28575

查看其他7个CD62E/CD62P抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

CD62E/CD62P Antibody in Flow Cytometry (Flow)

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CD62E/CD62P Antibody (MA5-28575) in Flow

Flow cytometry analysis of CD62E/CD62P in PMA and ionomycin stimulated human endothelial cell line HUV-EC-C. Cells were stained with CD62E/CD62P Monoclonal Antibody (1.2B6), PE-Cyanine5 (Product # MA5-28575).

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Immunogen image

Immunogen Image CD62E/CD62P Monoclonal Antibody (1.2B6), PE-Cyanine5

产品信息

MA5-28575

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

3 µL/10^6 cells

产品规格

种属反应

Human, Pig

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

1.2B6

抗原

TNF stimulated human endothelial cells

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偶联物

PE-Cyanine5 PE-Cyanine5 PE-Cyanine5

激发/发射光谱

568/666 nm 查看光谱

形式

Liquid

浓度

0.05 mg/mL

纯化类型

purified

保存液

PBS, pH 7.1, with proprietary stabilizer

内含物

<0.1% sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_2745534

靶标信息

CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD62 antigen-like family member E; CD62 antigen-like family member P; CD62E; CD62P; CD62P; CD62 homolog; E-selectin; ELAM-1; endothelial adhesion molecule 1; Endothelial leukocyte adhesion molecule 1; GMP-140; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; LECAM-2; LECAM-3; LECAM2; LECAM3; leukocyte endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 3; P-selectin; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; RP1-117P20.2; selectin E (endothelial adhesion molecule 1); selectin P (granule membrane protein 140kDa, antigen CD62)

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基因别名: CD62; CD62E; CD62P; ELAM; ELAM1; ESEL; GMP140; GMRP; GRMP; LECAM2; LECAM3; PADGEM; PSEL; SELE; SELP

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UniProt ID: (Human) P16581, (Pig) P98110, (Human) P16109

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Entrez Gene ID: (Human) 6401, (Pig) 397508, (Pig) 397150, (Human) 6403

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功能