Invitrogen

CD8/CD45RA Antibody Cocktail, FITC, PE

Name: CD8\/CD45RA Antibody Cocktail, FITC, PE
Brand: Invitrogen
SKU: MA1-12229

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA1-12229

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Cocktail

类型

Antibody

克隆号

17D8, BHKG-2

抗原

human peripheral blood monocytes from a rheumatoid arthritis patient and human peripheral blood T lymphocytes

偶联物

FITC , PE FITC , PE FITC , PE

形式

Liquid

纯化类型

Protein A/G

保存液

PBS with 0.2% carrier protein

内含物

0.08% sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_1073430

产品详细信息

This antibody is a monoclonal mixture of FITC-conjugated CD8 (clone 17D8, isotype IgG1) and PE-conjugated CD45RA (clone BHKG-2, isotype IgG1).

靶标信息

CD8 molecule is composed of two chains termed alpha and beta. CD8 is found on a T cell subset of normal cytotoxic / suppressor cells which make up approximately 20 to 35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15 to 30% of bone marrow cells. CD45 Leukocyte Common Antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: CD45; CD45 antigen; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8a; CD8alpha; CD8b; CD8beta; L-CA; Leu-2; Leu2 T-lymphocyte antigen; Leukocyte common antigen; OKT8 T-cell antigen; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Receptor-type tyrosine-protein phosphatase C; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-lymphocyte differentiation antigen T8/Leu-2; T200; T200 glycoprotein; T200 leukocyte common antigen; T8 T-cell antigen

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基因别名: B220; CD45; CD45R; CD8; CD8A; CD8B; CD8B1; GP180; L-CA; LCA; LEU2; LY3; LY5; LYT3; MAL; p32; P37; PTPRC; T200

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UniProt ID: (Human) P01732, (Human) P10966, (Human) P08575

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Entrez Gene ID: (Human) 925, (Human) 926, (Human) 5788

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功能