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Invitrogen
CD96v2 Monoclonal Antibody (628226)
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产品信息
MA5-61637
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
628226
抗原
Mouse myeloma cell line NS0-derived recombinant human CD96v2, Lys25-Asp501
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
CD96v2 is a splice variant of the CD96 gene, which encodes a protein involved in the immune system, particularly in the regulation of natural killer (NK) cells and T cells. CD96, also known as Tactile, is a member of the immunoglobulin superfamily and functions as an immune checkpoint receptor. It plays a role in the adhesion and interaction between NK cells and target cells, as well as in the modulation of NK cell cytotoxic activity. The variant CD96v2 may have distinct functional properties compared to the canonical form, potentially influencing immune responses in different ways. CD96 and its variants are of significant interest in cancer immunotherapy, as they can impact tumor immune surveillance and the effectiveness of NK cell-mediated tumor cell killing. Targeting CD96, including its splice variants like CD96v2, offers a promising strategy for enhancing anti-tumor immune responses. Understanding the specific roles and mechanisms of CD96v2 in immune regulation is crucial for developing novel therapeutic approaches aimed at boosting the immune system's ability to combat cancer and other diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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