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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4F2 cell-surface antigen heavy chain; 4F2hc; antigen identified by monoclonal antibodies 4F2; CD98 antigen; CD98 heavy chain; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3 member 2; type II transmembrane protein; unnamed protein product
基因别名: 4F2; 4F2HC; Cd98; Ly-10; Ly-m10; Ly10; Mdu1; Mgp-2hc; NACAE
UniProt ID: (Rat) Q794F9, (Mouse) P10852
Entrez Gene ID: (Rat) 50567, (Mouse) 17254