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Clone M026 detects 30 and 32 kDa* bands corresponding to the molecular mass of the short and long forms of CD99 on SDS-PAGE immunoblots of human A431, LNCaP, MDA-MB-231, A549, and MeWo cell lysates, as well as mouse LL2 lung carcinoma. The antibody can be used for multiple applications including ELISA capture, western blot, immunocytochemistry, and immunoprecipitation. In addition, the antibody labels live, unfixed MeWo cells.
CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 12E7; antigen identified by monoclonal 12E7, Y homolog; antigen identified by monoclonal antibodies 12E7, F21 and O13; CD99; CD99 antigen; cell surface antigen 12E7; cell surface antigen HBA-71; cell surface antigen O13; E2 antigen; MIC2 (monoclonal antibody 12E7); Paired immunoglobin-like type 2 receptor-ligand; PILR-L; Protein MIC2; surface antigen MIC2; T-cell surface glycoprotein E2
基因别名: 1110061M03Rik; 2410026K10Rik; CD99; D4; HBA71; MIC2; MIC2X; MIC2Y; MSK5X; pilr-1; Pilr-l; Pilrl
UniProt ID: (Human) P14209, (Mouse) Q8VCN6
Entrez Gene ID: (Human) 4267, (Rat) 652929, (Mouse) 673094