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Invitrogen
CDC42SE2 Monoclonal Antibody (OTI11F7)
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CDC42SE2 Antibody (MA5-26954) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human colon tissue. To expose target proteins, heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min. Following antigen retrieval, tissues were probed with a CDC42SE2 monoclonal antibody (Product # MA5-26954) at a dilution of 1:150.
产品信息
MA5-26954
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI11F7
抗原
Full length human recombinant protein of CDC42SE2 produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC42 small effector protein 2; non-kinase Cdc42 effector protein SPEC2; Small effector of CDC42 protein 2
基因别名: CDC42SE2; SPEC2
UniProt ID: (Human) Q9NRR3
Entrez Gene ID: (Human) 56990
