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Invitrogen
CDH17 Recombinant Rabbit Monoclonal Antibody (9X2S3)
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CDH17 Antibody (MA5-38141) in IHC (P)
Immunohistochemical analysis of CDH-17 was performed using formalin-fixed paraffin-embedded human colon tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58) diluted to 1X solution in water in a decloaking chamber at 110°C for 15 min. Following antigen ret... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38141
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9X2S3
抗原
Synthetic Peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2-7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
靶标信息
CDH17 gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BILL-cadherin; Cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; FLJ26931; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; LI cadherin; LI-cadherin; LI-cadherin; cell-cell adhesion molecule; liver-intestine cadherin; MGC138218; MGC142024; P130; unnamed protein product
基因别名: CDH16; HPT-1; HPT-1/LI; HPT1
UniProt ID: (Human) Q12864, (Mouse) Q9R100
Entrez Gene ID: (Human) 1015, (Mouse) 12557
cell morphogenesis
germinal center B cell differentiation
marginal zone B cell differentiation
cell-cell junction assembly
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
integrin-mediated signaling pathway
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell migration
B cell differentiation
positive regulation of integrin activation by cell surface receptor linked signal transduction
adherens junction organization
cell-cell adhesion mediated by cadherin
spleen development
transmembrane transport
cell-cell adhesion
T cell mediated immunity
oligopeptide transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
