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Abnova
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQEVSEYLS QNPRVAAWVE ALRCDGETDK HWRHRRDFLL RNAGDLAPAG GAASASTDEA ADAESGTRNR QLQQLISFSM AWANHVFLGC RYPQKVMDKI LSMAEGIKVT DAPTYTTRDE LVAKVKKRGI SSSNEGVEEP SKKRVIEGKN SSAVEQDHAK TSAKTERASA QQENSSTCIG SAIKSESGNS ARSSGISSQN SSTSDGDRSV SSQSSSSVSS QVTTAGSGKA SEAEAPDKHG SSFVSLLKSS VNSHMTQSTD SRQQSGSPKK SALEGSSASA SQSSSEIEVP LLGSSGSSEV ELPLLSSKPS SETASSGLTS KTSSEASVSS SVAKNSSSSG TSLLTPKSSS STNTSLLTSK STSQVAASLL ASKSSSQTSG SLVSKSTSLA SVSQLASKSS SQTSTSQLPS KSTSQSSESS VKFSCKLTNE DVKQKQPFFN RLYKTVAWKL VAVGGFSPNV NHGELLNAAI EALKATLDVF FVPLKELADL PQNKSSQESI VCELRCKSVY LGTGCGKSKE NAKAVASREA LKLFLKKKVV VKICKRKYRG SEIEDLVLLD EESRPVNLPP ALKHPQELL
CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: collaborates/cooperates with ARF (alternate reading frame) protein; collaborator of ARF; unnamed protein product; XRN2 binding domain containing 2
基因别名: XTBD2
UniProt ID: (Human) Q9NXV6
Entrez Gene ID: (Human) 55602