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Rockland
CDX2 Polyclonal Antibody
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FIGURE: 1 / 3
CDX2 Antibody (600-401-AH2) in ICC/IF
Immunofluorescence Microscopy of CDX2 antibody. Tissue: Rat brain cells. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: CDX2 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: CDX2 is nuclear. Staining: CDX2 as red fluorescent signal.
Product Details
600-401-AH2
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-CDX2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide near the C-terminus of human CDX2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
Gene Aliases: Cdx-2; CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626, (Mouse) P43241
Entrez Gene ID: (Human) 1045, (Mouse) 12591, (Rat) 66019
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
DNA binding
double-stranded DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
trophectodermal cell differentiation
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
endosome to lysosome transport
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
labyrinthine layer development
blastocyst development
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
pattern specification process
anterior/posterior pattern specification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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