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NeoBiotechnologies
CDw17 (Lactosylceramide or LacCer) Monoclonal Antibody (HuLy-m13)
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产品信息
MSM1-1088-P1BX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgM, kappa
分类
Monoclonal
类型
Antibody
克隆号
HuLy-m13
抗原
β-2 Microglobulin associated proteins from a detergent lysate of human PBL
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
CDw17, also known as Lactosylceramide (LacCer) or CD17, is a glycosphingolipid present on the surface of various cell types, including leukocytes, erythrocytes, and endothelial cells. It serves as a significant component of the cell membrane, involved in cell-cell interactions, cell adhesion, and signal transduction. Lactosylceramide is synthesized by the enzyme B-1,4-galactosyltransferase, which adds a galactose molecule to glucosylceramide. It acts as a precursor for more complex glycosphingolipids, playing critical roles in numerous physiological processes and immune responses. CDw17 is implicated in several pathological conditions, including atherosclerosis, cancer, and inflammatory diseases. In cancer, CDw17 acts as a mediator for tumor cell adhesion, invasion, and metastasis, making it a potential target for therapeutic intervention. Additionally, due to its role in the immune system, modulation of Lactosylceramide levels can influence immune cell functions and inflammatory responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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