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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CEACAM6/CD66c.
CEA Cell Adhesion Molecule 6 (CEACAM6) belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. CEACAM6 affects the sensitivity of tumor cells to adenovirus infection. The acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66c; CEACAM-1; CEACAM-3; CEACAM-5; CEACAM-6; CGM1; Cluster of Differentiation 66c; Non-specific crossreacting antigen; Normal cross-reacting antigen; pan CEACAM
基因别名: CD66c; CEACAM6; CEAL; NCA
UniProt ID: (Human) P40199
Entrez Gene ID: (Human) 4680