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Invitrogen
CELA1 Polyclonal Antibody
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产品信息
PA5-69813
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide corresponding to a region of mouse CELA1 (aa 80-129).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 92%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 85%; Rabbit: 86%; Rat: 100%
靶标信息
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 (ELA1) expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chymotrypsin-like elastase family member 1; elastase 1, pancreatic; Elastase-1
基因别名: 1810009A17Rik; 1810062B19Rik; Cela1; Ela-1; Ela1; PC-TsF
UniProt ID: (Mouse) Q91X79
Entrez Gene ID: (Mouse) 109901
negative regulation of transcription from RNA polymerase II promoter
proteolysis
inflammatory response
post-embryonic development
Wnt signaling pathway
exocrine pancreas development
multicellular organism growth
regulation of cell proliferation
regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
digestive system development
pancreas morphogenesis
