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Invitrogen
CELSR2 Polyclonal Antibody
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产品信息
PA5-33422
产品规格
种属反应
Bovine,
Dog,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CELSR2 / EGFL2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Bovine, Dog, Panda (100%) Elephant, Rabbit (95%) Gibbon, Rat (90%) Mouse (85%).
靶标信息
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion G protein-coupled receptor C2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; Epidermal growth factor-like protein 2; Flamingo homolog 3; FLJ34118; FLJ42737; FLJ45143; FLJ45845; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3
基因别名: ADGRC2; CDHF10; CELSR2; EGFL2; Flamingo1; KIAA0279; MEGF3
UniProt ID: (Human) Q9HCU4
Entrez Gene ID: (Human) 1952, (Bovine) 538194, (Dog) 479916
regulation of transcription, DNA-templated
homophilic cell adhesion via plasma membrane adhesion molecules
G-protein coupled receptor signaling pathway
spermatogenesis
Wnt signaling pathway
neural plate anterior/posterior regionalization
regulation of cell-cell adhesion
dendrite morphogenesis
Wnt signaling pathway, planar cell polarity pathway
