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Invitrogen
CELSR2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-50591
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human cadherin, EGF LAG seven-pass G-type receptor 2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.6 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total CELSR2 protein.
靶标信息
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cadherin EGF LAG seven-pas G-type receptor 2; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); EGF-like protein 2; Epidermal growth factor-like protein 2; Flamingo homolog 3; flamingo-like protein celsr2; Flamingo1; FLJ34118; FLJ42737; FLJ45143; FLJ45845; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; Multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin
基因别名: CDHF10; CELSR2; EGFL2; KIAA0279; MEGF3
Entrez Gene ID: (Rat) 83465
neuron migration
cilium movement
regulation of transcription, DNA-templated
homophilic cell adhesion via plasma membrane adhesion molecules
G-protein coupled receptor signaling pathway
spermatogenesis
Wnt signaling pathway
ventricular system development
neural plate anterior/posterior regionalization
regulation of cell-cell adhesion
regulation of protein localization
cerebrospinal fluid secretion
cilium assembly
dendrite morphogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
