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Invitrogen
CEP41 Polyclonal Antibody
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图: 1 / 2
CEP41 Antibody (PA5-103727) in ICC/IF
Immunocytochemistry analysis of CEP41 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CEP41 polyclonal antibody (Product # PA5-103727) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103727
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CEP41(Accession Q9BYV8), corresponding to amino acid residues D182-A232.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CEP41.
靶标信息
Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP41 (centrosomal protein of 41 kDa) gene encodes a protein of 373 amino acids that is alternatively spliced into 4 isoforms. Isoforms 1 and 4 are expressed in testis, as well as in and fetal brain and liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Centrosomal protein of 41 kDa; Cep41; testis specific gene A14; testis specific, 14; Testis-specific gene A14 protein
基因别名: 1700017E11Rik; 2810431D15Rik; CEP41; TSGA14
UniProt ID: (Mouse) Q99NF3, (Rat) Q4KM37
Entrez Gene ID: (Mouse) 83922, (Rat) 500069
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