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Abnova
CER1 Polyclonal Antibody, MaxPab™
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CER1 Antibody (H00009350-B01P) in WB
Western Blot analysis of CER1 expression in transfected 293T cell line (H00009350-T01) by CER1 MaxPab polyclonal antibody.
Lane 1: CER1 transfected lysate(29.37 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CER1 transfected lysate(29.37 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00009350-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CER1 (AAH69491.1, 1 a.a. approximately 267 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MHLLLFQLLV LLPLGKTTRH QDGRQNQSSL SPVLLPRNQR ELPTGNHEEA EEKPDLFVAV PHLVGTSPAG EGQRQREKML SRFGRFWKKP EREMHPSRDS DSEPFPPGTQ SLIQPIDGMK MEKSPLREEA KKFWHHFMFR KTPASQGVIL PIKSHEVHWE TCRTVPFSQT ITHEGCEKVV VQNNLCFGKC GSVHFPGAAQ HSHTSCSHCL PAKFTTMHLP LNCTELSSVI KVVMLVEECQ CKVKTEHEDG HILHAGSQDS FIPGVSA
靶标信息
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cerberus; cerberus 1, cysteine knot superfamily, homolog; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; MGC119894; MGC119895; MGC96951
基因别名: CER1; DAND4
UniProt ID: (Human) O95813
Entrez Gene ID: (Human) 9350
ureteric bud development
growth plate cartilage chondrocyte proliferation
gastrulation
nervous system development
negative regulation of cell proliferation
anterior/posterior axis specification
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
bone mineralization
BMP signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
sequestering of BMP in extracellular matrix
cell migration involved in gastrulation
determination of dorsal identity
determination of heart left/right asymmetry
cellular response to BMP stimulus
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of mesoderm development
