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Invitrogen
CERK Polyclonal Antibody
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CERK Antibody (PA5-109517) in WB
Western blot analysis of CERK in extracts of various cell lines. Samples were incubated with CERK Polyclonal antibody (Product # PA5-109517) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-109517
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human CERK (NP_073603.2).
偶联物
形式
Liquid
浓度
2.89 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CRRSPRGLSP AAHLGDGSSD LILIRKCSRF NFLRFLIRHT NQQDQFDFTF VEVYRVKKFQ FTSKHMEDED SDLKEGGKKR FGHICSSHPS CCCTVSNSSW NCDGEVLHSP AIEVRVHCQL VRLFARGIEE NPKPDSHS
靶标信息
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 ).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acylsphingosine kinase; Ceramide kinase; CERK antibody; hCERK; Lipid kinase 4; lipid kinase LK4; LK4; mCERK
基因别名: AI848610; CERK; D330016D08Rik; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4; mKIAA1646
UniProt ID: (Human) Q8TCT0, (Mouse) Q8K4Q7
Entrez Gene ID: (Human) 64781, (Mouse) 223753, (Rat) 300129
