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Agrisera
CERK1/Chitin elicitor receptor kinase 1 Polyclonal Antibody
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CERK1/Chitin elicitor receptor kinase 1 Antibody (AS16-4037) in WB
Total protein from 16-day old Arabidopsis thaliana Col-0 (wild-type) and cerk 1-2 null mutant (Cao et al., 2014). Total protein was extracted using Buffer H (Heese et al., 2007; La Montagne et al., 2016) except that 40 n M Calyculin was used. 70 µg of total protein was denatured at 65°C for 5 min, separated on an 8% SDS-PAGE and transferred for 1 h using a tank transfer system to nitrocellulose membrane. Bl... View More
产品信息
AS16-4037
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana RPS4 sequence.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
CERK1, also called chitin elicitor receptor kinase 1, is a plant pattern recognition receptor that detects chitin fragments from fungal cell walls to initiate innate immune signaling. It is a LysM domain receptor kinase at the plasma membrane that binds chitin and forms complexes with co receptors, leading to phosphorylation events that activate MAP kinases, calcium influx, and reactive oxygen species production. CERK1 triggers transcriptional reprogramming, callose deposition, and defense gene expression, enhancing resistance to fungal pathogens while balancing growth through crosstalk with hormones such as salicylic acid, jasmonate, and ethylene. Variants and homologs across species also perceive related carbohydrate signals such as peptidoglycan, shaping broad microbe associated molecular pattern recognition. Genetic disruption of CERK1 reduces chitin responsiveness and increases susceptibility, underscoring its central role in early cell surface immune surveillance in plants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AtCERK1; AtLYK1; chitin elicitor receptor kinase 1; LYK1; LYSM DOMAIN RECEPTOR-LIKE KINASE 1; LYSM RLK1; LysM-containing receptor-like kinase 1
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