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Invitrogen
CES2 Polyclonal Antibody
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CES2 Antibody (PA5-47715) in WB
Western blot analysis of CES2 in mouse liver tissue. Samples were incubated in CES2 polyclonal antibody (Product # PA5-47715) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for Carboxylesterase 2/CES2 at approximately 58-62 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47715
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Carboxylesterase 2/CES2 Gln27-Lys557 (predicted)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 30% cross-reactivity with recombinant human CES2 is observed and approximately 5% cross-reactivity with recombinant mouse (rm) CES3 and rmCES5 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACH M1; Acylcarnitine hydrolase; acylcarnitine hydrolase M1; Carboxylesterase 2; carboxylesterase 2E; carboxylesterase 5; carboxylesterase ML3; Carboxylic ester hydrolase; CES 2; CES-2; P iCE; Peroxisome proliferator-inducible acylcarnitine hydrolase; Pyrethroid hydrolase Ces2e
基因别名: 9030624L02Rik; ACH M1; CES 2; Ces2; ces2A3; Ces2c; Ces2e; Ces5
UniProt ID: (Mouse) Q91WG0, (Mouse) Q8BK48
Entrez Gene ID: (Mouse) 234671, (Mouse) 234673
