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Abnova
CFHR1 Monoclonal Antibody (4D7)
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产品信息
H00003078-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
4D7
抗原
CFHR1 (AAH16755.1, 19 a.a. approximately 330 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: EATFCDFPKI NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRLCF FPFVENGHSE SSGQTHLEGD TVQIICNTGY RLQNNENNIS CVERGWSTPP KCRSTDTSCV NPPTVQNAHI LSRQMSKYPS GERVRYECRS PYEMFGDEEV MCLNGNWTEP PQCKDSTGKC GPPPPIDNGD ITSFPLSVYA PASSVEYQCQ NLYQLEGNKR ITCRNGQWSE PPKCLHPCVI SREIMENYNI ALRWTAKQKL YLRTGESAEF VCKRGYRLSS RSHTLRTTCW DGKLEYPTCA KR
靶标信息
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: complement factor H-related 1 pseudogene; Complement factor H-related protein 1; FHL-1; FHR-1; H factor (complement)-like 1; H factor (complement)-like 2; H factor-like protein 1; H-factor-like 1; H36
基因别名: CFHL; CFHL1; CFHL1P; CFHR1; CFHR1P; FHR1; H36-1; H36-2; HFL1; HFL2
UniProt ID: (Human) Q03591
Entrez Gene ID: (Human) 3078
