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Invitrogen
CFHR4 Monoclonal Antibody (640212)
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CFHR4 Antibody (MA5-24288) in ICC/IF
Immunocytochemistry analysis of CFHR4 in immersion fixed human peripheral blood mononuclear cells (PBMC). Samples were incubated in CFHR4 monoclonal antibody (Product # MA5-24288) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
产品信息
MA5-24288
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
640212
抗原
Sf 21-derived recombinant human Complement Factor H-related 4/CFHR4 Glu20-Glu331
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, no cross-reactivity with recombinant human (rh) CFHR1, rhCFHR2, or rhCFHR5 is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: complement factor H; complement factor H-related 4; Complement factor H-related protein 4; FHR-4
基因别名: CFHL4; CFHR4; FHR-4; FHR4
UniProt ID: (Human) Q92496
Entrez Gene ID: (Human) 10877
