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Invitrogen
CGRPR (Erenumab Biosimilar) Recombinant Human Monoclonal Antibody
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CGRPR (Erenumab Biosimilar) Antibody (MA5-42108) in SDS-PAGE
SDS-PAGE analysis of CGRPR (Erenumab Biosimilar). Samples were run under reducing (R) and non-reducing (NR) conditions using CGRPR (Erenumab Biosimilar) monoclonal antibody (Product # MA5-42108). The purity of the protein is greater than 95%.
产品信息
MA5-42108
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG2, lambda
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human CALCRL/CGRP-R
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.12 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
The Calcitonin Gene-Related Peptide Receptor (CGRPR) primarily refers to the receptor complex involving the gene CALCRL (calcitonin receptor-like receptor) and the receptor activity-modifying protein (RAMP1). This complex is vital in the transmission of signals for the peptide hormone calcitonin gene-related peptide (CGRP). CALCRL is located on chromosome 2 and is part of the G protein-coupled receptor family. The functional receptor is significant in mediating vascular smooth muscle cell relaxation and is thus involved in various physiological responses, including vasodilation, pain transmission, and neurogenic inflammation. The receptor’s activation by CGRP plays an essential role in migraine pathophysiology by promoting vasodilation and influencing pain signaling pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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