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Invitrogen
CHAC1 Polyclonal Antibody
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CHAC1 Antibody (PA5-31762) in WB
Western Blot using CHAC1 Polyclonal Antibody (Product # PA5-31762). Sample (30 µg of whole cell lysate). Lane A: HeLa treat tunicamycin (4 µg/mL). 12% SDS PAGE. CHAC1 Polyclonal Antibody (Product # PA5-31762) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-31762
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CHAC1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa(4ug/ml TM_12hr, 4ug/ml TM_24hr)(30ug).
Predicted reactivity: Mouse (94%), Rat (96%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Pro-apoptotic component of the unfolded protein response pathway. May mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Blocks Notch protein; Botch; Cation transport regulator-like protein 1; ChaC glutathione-specific gamma-glutamylcyclotransferase 1; ChaC, cation transport regulator homolog 1; ChaC, cation transport regulator-like 1; Gamma-GCG 1; gamma-GCT acting on glutathione homolog 1; Glutathione-specific gamma-glutamylcyclotransferase 1
基因别名: 1810008K03Rik; BOTCH; CHAC1
UniProt ID: (Human) Q9BUX1, (Mouse) Q8R3J5
Entrez Gene ID: (Human) 79094, (Mouse) 69065
glutathione biosynthetic process
response to unfolded protein
Notch signaling pathway
negative regulation of protein processing
neurogenesis
negative regulation of Notch signaling pathway
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
apoptotic process
nervous system development
