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Invitrogen
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Immunogen sequence: LPKSALFSES QKAVELGDEL QIDAIDDQKC DILVQEELLA SPKKLLEDTL FPSSKKLKKD NQESSDAELS SSEYIKTDLD AMDIKGQESS SDQEQVDVES IDFSKENKMD MTSPEQSRNV LQFTEEKEAF ISEEEIAKYM KRGKGKYYCK ICCCRAMKKG AVLHHLVNKH NVHSPYKCTI CGKAFLLESL LKNHVAAHGQ SLLKCPRCNF ESNFPRGFKK HLTHCQSRHN EEANKKLMEA LEPPLEEQQI; Positive Samples: U-87MG, A-431, Jurkat ; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle
Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Chromosome alignment-maintaining phosphoprotein 1; Zinc finger protein 828
基因别名: C13orf8; CAMP; CHAMP; CHAMP1; KIAA1802; MRD40; ZNF828
UniProt ID: (Human) Q96JM3
Entrez Gene ID: (Human) 283489