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Invitrogen
CHD9 Polyclonal Antibody
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CHD9 Antibody (PA5-88379) in WB
Western blot analysis of CHD9 in extracts of various cell lines. Samples were incubated with CHD9 Polyclonal antibody (Product # PA5-88379) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-88379
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 85-190 of human CHD9 (NP_0794104)
偶联物
形式
Liquid
浓度
1.27 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SFGSPAEHVL SPHSQFNCSP IHPQNQPNGL FPDVSDGSPM WGHQTATTIS NQNGSPFHQQ GHSHSMHQNK SFVAHHDFAL FQANEQQTQC TSLRSQQNRN NLNPGQ; Positive Samples: U-87MG, HeLa, Jurkat, A-549, 293t, K-562, Mouse kidney; Cellular Location: Cytoplasm, Nucleus
靶标信息
CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2 or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family. The CHD family of proteins are ATP-dependent chromatin remodeling enzymes which combine chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability. Localized to the cytoplasm and the nucleus, CHD9 contains two chromodomains, one ATPbinding helicase domain and one C-terminal helicase domain. Chromodomains are protein regions of about 40-50 amino acid residues found in proteins associated with chromatin remodeling and manipulation. The domain is highly conserved among both plants and animals and is found in a large variety of proteins from many genomes. CHD9 acts as a transcriptional coactivator for PPARα and may also be an ATP-dependent chromatin remodeling protein. CHD9 is widely expressed at low levels and is present as three isoforms produced by alternative splicing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-dependent helicase CHD9; BC022889; CHD-9; chromatin remodeling factor CHROM1; Chromatin-related mesenchymal modulator; Chromatin-remodeling factor CHROM1; Chromodomain-helicase-DNA-binding protein 9; ciprofibrate bound protein p240; ciprofibrate-bound protein PRIC320; CReMM; FLJ12178; Kismet homolog 2; Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; PPAR-alpha-interacting complex protein 320 kDa; PPAR{gamma}-interacting cofactor 320 kDa; proteinx0008
基因别名: 1810014J18Rik; 9030205D12Rik; A330063D19Rik; AD-013; AD013; CHD-9; CHD9; CReMM; KIAA0308; KISH2; mKIAA0308; PRIC320; x0008
UniProt ID: (Human) Q3L8U1, (Mouse) Q8BYH8
Entrez Gene ID: (Human) 80205, (Mouse) 109151
