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Invitrogen
CHI3L1 Recombinant Rabbit Monoclonal Antibody (7T1R3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-51223
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7T1R3
抗原
Synthetic peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: PGRFTKEAGT LAYYEICDFL RGATVHRILG QQVPYATKGN QWVGYDDQES VKSKVQYLKD RQLAGAMVWA LDLDDFQGSF CGQDLRFPLT NAIKDALAAT
靶标信息
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39 kDa synovial protein; breast regression protein 39; cartilage glycoprotein 39; CGP-39; CGP39; Chi3l1; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-like 1; DKFZp686N19119; FLJ38139; GP-39; hCGP39; unnamed protein product; YKL-40
基因别名: ASRT7; Brp39; CGP-39; Chil1; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YK-40; YKL-40; YKL40; YYL-40
UniProt ID: (Human) P36222, (Mouse) Q61362
Entrez Gene ID: (Human) 1116, (Mouse) 12654
carbohydrate metabolic process
chitin catabolic process
apoptotic process
inflammatory response
response to mechanical stimulus
lung development
positive regulation of interleukin-8 production
transforming growth factor beta1 production
response to tumor necrosis factor
positive regulation of angiogenesis
cartilage development
positive regulation of protein kinase B signaling
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
response to interleukin-6
cellular response to tumor necrosis factor
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
