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Invitrogen
CHI3L1 Monoclonal Antibody (CL12314)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-44169
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL12314
抗原
Recombinant protein corresponding to Human CHI3L1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.95 mg/mL
规格
95 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: GQDLRFPLTN AIKDALAAT
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 71%.
靶标信息
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39 kDa synovial protein; cartilage glycoprotein 39; CGP39; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1 (cartilage glycoprotein-39); DKFZp686N19119; FLJ38139; hCGP39; unnamed protein product
基因别名: ASRT7; CGP-39; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YK-40; YKL-40; YKL40; YYL-40
UniProt ID: (Human) P36222
Entrez Gene ID: (Human) 1116
carbohydrate metabolic process
chitin catabolic process
apoptotic process
inflammatory response
response to mechanical stimulus
lung development
positive regulation of interleukin-8 production
transforming growth factor beta1 production
response to tumor necrosis factor
positive regulation of angiogenesis
cartilage development
positive regulation of protein kinase B signaling
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
response to interleukin-6
cellular response to tumor necrosis factor
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
