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CHIT1 Antibody (PA5-109528) in IHC (P)
Immunohistochemistry analysis of CHIT1 in paraffin-embedded human normal stomach. Samples were incubated with CHIT1 Polyclonal antibody (Product # PA5-109528) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-109528
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).
偶联物
形式
Liquid
浓度
3.55 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854939
产品详细信息
Immunogen sequence: SWEKVTGHNS PLYKRQEESG AAASLNVDAA VQQWLQKGTP ASKLILGMPT YGRSFTLASS SDTRVGAPAT GSGTPGPFTK EGGMLAYYEV CSWKGATKQR IQDQKVPYIF RDNQWVGFDD VESFKTKVSY LKQKGLGGAM VWALDLDDFA GFSCNQGRYP LIQTLRQELS LPYLPSGTPE LEVPKPGQPS EPEHGPSPGQ DTFCQGKADG LYPNPRERSS FYSCAAGRLF QQSCPTGLVF SNSCKCCTWN
靶标信息
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: chitinase 1 (chitotriosidase); Chitinase-1; Chitotriosidase; Chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
基因别名: 2300002L19Rik; CHI3; CHIT; CHIT1; CHITD
UniProt ID: (Human) Q13231, (Mouse) Q9D7Q1
Entrez Gene ID: (Human) 1118, (Mouse) 71884
