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Invitrogen
CHL1 Polyclonal Antibody
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CHL1 Antibody (PA5-115014) in ICC/IF
Immunocytochemistry analysis of CHL1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115014) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
产品信息
PA5-115014
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CHL1(Accession O00533), corresponding to amino acid residues G1168-A1208.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CHL1.
靶标信息
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. Several alternatively spliced transcript variants of this gene have been described, but their full length nature is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell adhesion molecule L1-like; Cell adhesion molecule with homology to L1CAM; cell adhesion molecule with homology to L1CAM (close homolog of L1); cell adhesion molecule with homology to L1CAM (close homologue of L1); Chl1-like protein; Close homolog of L1; L1 cell adhesion molecule 2; Neural cell adhesion molecule L1-like protein
基因别名: A530023M13Rik; AI465420; CALL; CHL1; L1CAM2; LICAM2
UniProt ID: (Human) O00533, (Mouse) P70232
Entrez Gene ID: (Human) 10752, (Rat) 89828, (Mouse) 12661
neuron migration
cell adhesion
signal transduction
axon guidance
adult locomotory behavior
axon regeneration
exploration behavior
negative regulation of neuron apoptotic process
cognition
homophilic cell adhesion via plasma membrane adhesion molecules
neuron projection development
multicellular organism development
nervous system development
cell differentiation
